“When you run out of questions, you run out of hope.”

“You spend your whole life looking for answers, because you think the next answer will change something, maybe make you a little less miserable.

“And you know that when you run out of questions, you don’t just run out of answers.

“You run out of hope.”

— Number 13 to House, M.D. , “You Don’t Want To Know,” Season 4, Episode 8